Picayune is the largest city in Pearl River County, Mississippi. Estimates from July 2023 show the population at 11,784 for Picayune. The city was added to the New Orleans Metropolitan area in 2014 and is located approximately 1 hour from New Orleans, Hattiesburg, and Gulfport/Biloxi. The Stennis Space Center is 10 miles (16 km) away.

Discover Historic Downtown Picayune, MS and Experience the New South Old Charm that our community is known for. Check out Downtown Antique & Vintage, Art & Clothing Shops & Delicious Local Dining along with over 250 Artisans featuring Antique, Woodwork, Clothing, Jewelry along with a variety of food vendors to please every taste bud.